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Signal Transduction by Bastien D. Gomperts, Ijsbrand M. Kramer, Peter E.R. Tatham (Paperback, 2003)
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The_Book_Fountain (184039)
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About this product
Product Information
Signal Transduction now in paperback, is a text reference on cellular signalling processes. Starting with the basics, it explains how cells respond to external cues (hormones, cytokines, neurotransmitters, adhesion molecules, extracellular matrix, etc), and shows how these inputs are integrated and co-ordinated. The first half of the book provides the conceptual framework, explaining the formation and action of second messengers, particulary cyclic nucleotides and calcium, and the mediation of signal pathways by GTP-binding proteins. The remaining chapters deal with the formation of complex signalling cascades employed by cytokines and adhesion molecules, starting at the membrane and ending in the nucleus, there to regulate gene transcription. In this context, growth is an important potential outcome and this has relevance to the cellular transformations that underlie cancer. The book ends with a description at the molecular level of how signalling proteins interact with their environment and with each other through their structural domains. Each main topic is introduced with a historical essay, detailing the sources key observations and experiments that set the scence for recent and current work.Product Identifiers
PublisherElsevier Science Publishing Co Inc
ISBN-139780122896323
eBay Product ID (ePID)96583248
Product Key Features
Number of Pages440 Pages
Publication NameSignal Transduction
LanguageEnglish
SubjectBiology, Physics
Publication Year2003
TypeTextbook
AuthorBastien D. Gomperts, Ijsbrand M. Kramer, Peter E.R. Tatham
FormatPaperback
Dimensions
Item Height246 mm
Item Weight1238 g
Item Width189 mm
Additional Product Features
Country/Region of ManufactureUnited States
Title_AuthorIjsbrand M. Kramer, Peter E.R. Tatham, Bastien D. Gomperts
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