Additional Product Features
Intended AudienceScholarly & Professional
LCCN2004-054761
Reviews'Christian de Duve gives his readers generous transparency in laying bare his reasoning and in the aesthetics of his current attempt at hard and beautiful problems concerning the unitary features of life and their origin. Few books allow this continuity of thinking over sucha broad range of interrekated problems.' BioEssays, '... fine, incisive prose. ... [De Duve] takes us on a dazzling trip within a cell, providing a beautiful exposition of life's biochemical cycles, their elegance, equilibrium and evolution.' New Scientist, "This book is unquestionably for serious students of biology, biochemistry, and evolution, but anyone willing to work through the details will find a logical tour de force and a powerful illustration of the beauty of evolution." - Choice, "This volume is well written and readable, and I enjoyed de Duve's unique perspective on this difficult topic, which is invariably multidisciplinary...Singularities is an excellent book, and recommended reading for anyone interested in the fundamental questions of life and its origins." The Quarterly Review of Biology, S.Blair Hedges, Pennsylvania State University, "This volume is well written and readable, and I enjoyed de Duve's unique perspective on this difficult topic, which is invariably multidisciplinary...Singularities is an excellent book, and recommended reading for anyone interested in the fundamental questions of life and its origins." -The Quarterly Review of Biology, S. Blair Hedges, Pennsylvania State University, '… we should always be alert to the great problems, such as understanding the processes leading to the origin of life. Given past experience, such great questions will be solved - not by chance but by the prepared mind. This book is a start to preparing that mind.' Nature, '… fine, incisive prose. … [De Duve] takes us on a dazzling trip within a cell, providing a beautiful exposition of life's biochemical cycles, their elegance, equilibrium and evolution.' New Scientist, '... we should always be alert to the great problems, such as understanding the processes leading to the origin of life. Given past experience, such great questions will be solved - not by chance but by the prepared mind. This book is a start to preparing that mind.' Nature, '... fine, incisive prose. He takes us on a dazzling trip within a cell, providing a beautiful exposition of life's biochemical cycles, their elegance, equilibrium and evolution.' New Scientist, "This book is unquestionably for serious students of biology, biochemistry, and evolution, but anyone willing to work through the details will find a logical tour de force and a powerful illustration of the beauty of evolution." Choice
Dewey Edition22
IllustratedYes
Dewey Decimal576.8/3
Table Of Content1. Building blocks; 2. Homochirality; 3. Protometabolism; 4. ATP; 5. Electrons and protons; 6. Thioesters; 7. RNA; 8. Proteins; 9. DNA; 10. Membranes; 11. Protonmotive force; 12. Protometabolism revisited; 13. The LUCA; 14. The first fork; 15. Eukaryotes; 16. Oxygen; 17. Endosymbionts; 18. Multicellular organisms; 19. Homo; 20. Evolution revisited.
SynopsisErwin Schr dinger's What is Life? published 60 years ago, influenced much of the development of molecular biology. In this new book Christian De Duve, Nobel Laureate and pioneer of modern cell biology, presents a contemporary response to this classic, providing a sophisticated consideration of the key steps or bottlenecks that constrain the origins and evolution of life. De Duve surveys the entire history of life, including insights into the conditions that may have led to its emergence. He uses as landmarks the many remarkable singularities along the way, such as the single ancestry of all living beings, the universal genetic code, and the monophyletic origin of eukaryotes. The book offers a brief guided tour of biochemistry and phylogeny, from the basic molecular building blocks to the origin of humans. Each successive singularity is introduced in a sequence paralleling the hypothetical development of features and conditions on the primitive earth, explaining how and why each transition to greater complexity occurred., Erwin Schrödinger's What is Life? published 60 years ago, influenced much of the development of molecular biology. In this new book Christian De Duve, Nobel Laureate and pioneer of modern cell biology, presents a contemporary response to this classic, providing a sophisticated consideration of the key steps or bottlenecks that constrain the origins and evolution of life. De Duve surveys the entire history of life, including insights into the conditions that may have led to its emergence. He uses as landmarks the many remarkable singularities along the way, such as the single ancestry of all living beings, the universal genetic code, and the monophyletic origin of eukaryotes. The book offers a brief guided tour of biochemistry and phylogeny, from the basic molecular building blocks to the origin of humans. Each successive singularity is introduced in a sequence paralleling the hypothetical development of features and conditions on the primitive earth, explaining how and why each transition to greater complexity occurred., In this new book Christian De Duve, Nobel Laureate and pioneer of modern cell biology, presents a contemporary response to Erwin Schrodinger's classic What is Life? providing a sophisticated consideration of the key steps or bottlenecks that constrain the origins and evolution of life., Erwin Schr'dinger?'s What is Life? published 60 years ago, influenced much of the development of molecular biology. In this new book Christian De Duve, Nobel Laureate and pioneer of modern cell biology, presents a contemporary response to this classic, providing a sophisticated consideration of the key steps or bottlenecks that constrain the origins and evolution of life. De Duve surveys the entire history of life, including insights into the conditions that may have led to its emergence. He uses as landmarks the many remarkable singularities along the way, such as the single ancestry of all living beings, the universal genetic code, and the monophyletic origin of eukaryotes. The book offers a brief guided tour of biochemistry and phylogeny, from the basic molecular building blocks to the origin of humans. Each successive singularity is introduced in a sequence paralleling the hypothetical development of features and conditions on the primitive earth, explaining how and why each transition to greater complexity occurred.
LC Classification NumberQH325.D418 2005