Taste Mask Orodispersible Tablet of Metronidazole: Development ... (paperback)

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eBay item number:406231426321
Last updated on Sep 29, 2025 18:44:31 SGTView all revisionsView all revisions

Item specifics

Condition
Very Good: A book that has been read but is in excellent condition. No obvious damage to the cover, ...
ISBN
9783848442973
Category

About this product

Product Identifiers

Publisher
LAP Gmbh & Company KG
ISBN-10
3848442973
ISBN-13
9783848442973
eBay Product ID (ePID)
128506802

Product Key Features

Number of Pages
88 Pages
Language
English
Publication Name
Taste Mask Orodispersible Tablet of Metronidazole
Subject
Pharmacology
Publication Year
2012
Type
Textbook
Subject Area
Medical
Author
Aditya Nath Pandey, Anupam Jain, Suresh Kumar Sahu
Format
Trade Paperback

Dimensions

Item Height
0.2 in
Item Weight
5 Oz
Item Length
9 in
Item Width
6 in

Additional Product Features

Synopsis
Patients who have problems in swallowing encounter difficulties in taking tablets, particularly pediatric and geriatric patients. Such problems can be resolved by means of orodispersible tablets. These tablets disintegrate instantaneously when put on tongue, releasing the drug that dissolves or disperses in the saliva.Metronidazole is active against a wide variety of anaerobic protozoal parasites and anaerobic bacteria.The present study aim to prepare tablets that can rapidly disintegrate in oral cavity (orodispersible), another challenge with this model drug is to mask the bitter taste. Taste masking was achieved by using aminoalkyl methacrylate copolymer (Eudragit E-100) in the different ratio (1:2 and 1:3) by extrusion technique. The IR shows that there was no significant evidence for interaction between drug and polymers. Six formulations were prepared using taste masked granules and different disintegrants (LH-11) and Avicel PH-102 by varying concentration.

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plumcirclebooks

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