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Controlled Clinical Trials in Neurological Disease by Roger J. Porter (English)

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Item specifics

Condition
Brand New: A new, unread, unused book in perfect condition with no missing or damaged pages. See all condition definitionsopens in a new window or tab
ISBN-13
9781461288046
Book Title
Controlled Clinical Trials in Neurological Disease
ISBN
9781461288046
Series
Foundations of Neurology Ser.
Publication Year
2011
Type
Textbook
Format
Trade Paperback
Language
English
Publication Name
Controlled Clinical Trials in Neurological Disease
Author
Bruce S. Schoenberg
Item Length
9.3in
Publisher
Springer
Item Width
6.1in
Item Weight
25.1 Oz
Number of Pages
Xxiv, 440 Pages

About this product

Product Information

The evaluation of the efficacy and safety of a clinical tool, be it a diagnostic technique, a preventive methodology, or a therapeutic intervention, is an im- portant responsibility of physicians. The history of medicine is characterized by the authoritarianisms of teachers and of organizations giving way to the clinical experience of physicians; authoritarian dictum was replaced by case report and then by case series. As physicians learned to substitute the analysis of data for the inconsistencies of dictums and anecdotes, the problems of the case series as an investigative tool became more evident: patient selection criteria, measurements of outcome, significance of results, and extrapolation of conclusions to the community of patients. In response to these issues, the methodology of the controlled clinical trial has evolved and with it the instru- ments of study design and of biostatistics as aids to study design and data analysis. The medical - surgical armamentarium has evolved from being dependent solely upon the observations and conclusions of a skilled clinician to being constructed upon the systematic collection and evaluation of data by a team of skilled clinicians and their statistical colleagues: this is the controlled clinical trial. During the past two decades, the evaluation of clinical approaches to pre- vention and therapy has become particularly important to clinicians concerned with nervous system dysfunction. There has been and continues to be an explosion of information from the basic neurosciences and from the applica- tion of biotechnology to the nervous system.

Product Identifiers

Publisher
Springer
ISBN-10
1461288045
ISBN-13
9781461288046
eBay Product ID (ePID)
175755149

Product Key Features

Author
Bruce S. Schoenberg
Publication Name
Controlled Clinical Trials in Neurological Disease
Format
Trade Paperback
Language
English
Series
Foundations of Neurology Ser.
Publication Year
2011
Type
Textbook
Number of Pages
Xxiv, 440 Pages

Dimensions

Item Length
9.3in
Item Width
6.1in
Item Weight
25.1 Oz

Additional Product Features

Series Volume Number
1
Number of Volumes
1 Vol.
Lc Classification Number
Rc346-429.2
Reviews
'Cet ouvrage, rédigée par de nombreux experts et d'une manière fort critique, est certainement très précieux. Il mérite d'être lu et médité.' Acta Neurologica, 90, 1990 ' ... for any serious researcher. The book is recommended for all health care professionals who have an interest in neurological neurosurgical or neurorehabilitative research.' Brain Injury, 7:1, 'Cet ouvrage, rdige par de nombreux experts et d'une manire fort critique, est certainement trs prcieux. Il mrite d'tre lu et mdit.' Acta Neurologica, 90, 1990 ' ... for any serious researcher. The book is recommended for all health care professionals who have an interest in neurological neurosurgical or neurorehabilitative research.' Brain Injury, 7:1
Table of Content
I. Design of Controlled Clinical Trials.- 1. Clinical considerations.- 2. Initial statistical considerations.- 3. Statistical and epidemiological considerations.- II. Implementation and Interpretations of Controlled Clinical Trials (Example: Epilepsy).- 4. Perspective of the patient.- 5. Perspective of the participating investigator.- 6. Perspective of the clinical center.- 7. Perspective of the coordinating center.- 8. Perspective of the food and drug administration.- 9. Perspective of the pharmaceutical industry.- 10. Perspective of the insurance industry.- III. Applications of Controlled Clinical Trials to Diseases of the Nervous System.- 11. Cerebrovascular disease.- 12. Epilepsy.- 13. Movement disorders.- 14. Head and spinal cord injury.- 15. Headache.- 16. Peripheral neuropathy.- 17. Guillain-Barré: Plasmapheresis.- 18. Motor neuron disease.- 19. Myasthenia gravis.- 20. Muscular dystrophy.- 21. Multiple sclerosis.- 22. Brain tumors.- 23. Alzheimer's disease.- 24. Viral diseases: Herpes simplex encephalitis.- 25. Parasitic diseases.
Copyright Date
1990
Topic
Neurology, Life Sciences / Neuroscience
Dewey Decimal
616.8/0724
Intended Audience
Scholarly & Professional
Dewey Edition
20
Illustrated
Yes
Genre
Science, Medical

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