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kosystem Darm Special: Updates on Clostridium difficile by Jean-Paul Rambaud (Ge

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Item specifics

Condition: Brand New: A new, unread, unused book in perfect condition with no missing or damaged pages. See all condition definitionsopens in a new window or tab

ISBN-13: 9782287596407

Book Title: kosystem Darm Special

ISBN: 9782287596407

Subject Area: Medical

Publication Name: Ökosystem Darm Special

Publisher: Springer Paris

Item Length: 9.3 in

Subject: Gastroenterology

Publication Year: 1997

Type: Textbook

Format: Trade Paperback

Language: German

Item Height: 0.1 in

Author: J. Thomas Lamont

Item Weight: 12 Oz

Item Width: 6.1 in

Number of Pages: X, 142 Pages

About this product

Product Identifiers

Publisher

Springer Paris

ISBN-10

2287596402

ISBN-13

9782287596407

eBay Product ID (ePID)

203581424

Product Key Features

Number of Pages

X, 142 Pages

Language

German

Publication Name

Ökosystem Darm Special

Subject

Gastroenterology

Publication Year

1997

Type

Textbook

Subject Area

Medical

Author

J. Thomas Lamont

Format

Trade Paperback

Dimensions

Item Height

0.1 in

Item Weight

12 Oz

Item Length

9.3 in

Item Width

6.1 in

Additional Product Features

Intended Audience

Scholarly & Professional

Number of Volumes

1 vol.

Illustrated

Yes

Table Of Content

Table of contents / Table des matières / Inhaltsverzeichnis.- Clostridium difficile: clinical spectrum with emphasis on atypical clinical presentations.- Clostridium difficile infection in the elderly.- The clinical significance of Clostridium difficile infections in infants and children.- Nocosomial acquisition and risk factors for Clostridium difficile disease.- Prevalence and pathogenicity of Clostridium difficile. A French multicenter study.- Epidemiological markers of Clostridium difficile.- Recent advances in the structure and function of Clostridium difficile toxins.- Antibody response to Clostridium difficile toxins.- Laboratory methods for detecting the toxins of Clostridium difficile.- Updates on the management of Clostridium difficile associated intestinal disease.- Treatment of the recurrent Clostridium difficile diarrheal syndrome with Saccharomyces boulardii.- Mechanisms of Saccharomyces boulardii on Clostridium difficile infection.- Conclusion.

Synopsis

Jean-Claude Rambaud The place occupied today in basic and clinical research by intestinal disease related to Clostridium difficile is such that it is hard to remember that this range of disorders was completely identified only in 1977-1978, even though pieces of the puzzle had been identified ,much earlier. A brief historical review of the discovery of the enteropathogenicity of C. dif. ficile in man might thus be useful. The bacterium was described in 1935 in the stools of infants, using the name Bacillus difficilis [7]. U ntiI 1977, the microorganism, renamed C. difficile, considered to be of endogenous origin, was isolated only in rare cases of abscess or infection, most often unrelated to the digestive tract. Its role in genito-urinary infections [6] was not confirmed. However, the frequency of infant healthy carriers was recognized from the outset [7, 13]. Pseudo-membranous colitis (PMC) was described in 1883 following~ a gastroenterostomy. Many cases of this condition were published subsequently before the antibiotic era, describing various risk factors [4]. However the disease began to flourish only with the increasingly wide use of antibiotics. Antibiotic associated PMC was first described as an enterocolitis, though with little pathological evidence. It was principally related to the use of chloramphenicol and tetracyclines and attributed to proliferation of Staphylococcus aureus [11], a concept strengthened by the spectacular therapeutic action of vancomycin., Jean-Claude Rambaud The place occupied today in basic and clinical research by intestinal disease related to Clostridium difficile is such that it is hard to remember that this range of disorders was completely identified only in 1977-1978, even though pieces of the puzzle had been identified, much earlier. A brief historical review of the discovery of the enteropathogenicity of C. dif. ficile in man might thus be useful. The bacterium was described in 1935 in the stools of infants, using the name Bacillus difficilis 7]. U ntiI 1977, the microorganism, renamed C. difficile, considered to be of endogenous origin, was isolated only in rare cases of abscess or infection, most often unrelated to the digestive tract. Its role in genito-urinary infections 6] was not confirmed. However, the frequency of infant healthy carriers was recognized from the outset 7, 13]. Pseudo-membranous colitis (PMC) was described in 1883 following a gastroenterostomy. Many cases of this condition were published subsequently before the antibiotic era, describing various risk factors 4]. However the disease began to flourish only with the increasingly wide use of antibiotics. Antibiotic- associated PMC was first described as an enterocolitis, though with little pathological evidence. It was principally related to the use of chloramphenicol and tetracyclines and attributed to proliferation of Staphylococcus aureus 11], a concept strengthened by the spectacular therapeutic action of vancomycin.

LC Classification Number

RC799-869