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Dendritic Cells - 9783642090073
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Located in: Aldershot, United Kingdom
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Item specifics
- Condition
- Brand New: A new, unread, unused book in perfect condition with no missing or damaged pages. See all condition definitionsopens in a new window or tab
- Book Title
- Dendritic Cells
- ISBN
- 9783642090073
- Publication Year
- 2010
- Type
- Textbook
- Format
- Paperback
- Language
- English
- Publication Name
- Dendritic Cells
- Item Height
- 235mm
- Publisher
- Springer-Verlag Berlin AND Heidelberg Gmbh & Co. KG
- Item Width
- 155mm
- Subject
- Medicine
- Item Weight
- 569g
- Number of Pages
- 353 Pages
About this product
Product Information
The understanding of the role of dendritic cells (DCs) in immune responses has come a long way since Steinmann and colleagues described these cells in 1972. - tensive research during the intervening period has provided a good understanding of the complexity of the DC system and its pivotal role in immunity. It is also now clearer how different subsets of DCs interact and regulate each other and how DC populations affect the function of other cells of the immune system. The improved understanding of their role in immune response has led to the idea that modulation of DC functions by, for example, pharmacological agents could be used as a pot- tial therapeutic approach in some pathological conditions. The actual applicability and therapeutic potential of all these approaches is yet to be fully demonstrated but nonetheless, animal models of human diseases are proving to be very helpful in the evaluation of manipulated DCs as a new treatment in diseases like cancer, auto- munity or asthma. DCs are integral to the initiation and regulation of immune response (Banchereau et al. 2000). The outcome of antigen presentation by DCs is determined by their maturation status, which can be induced by their interaction with danger signals. To recognise a wide array of pathogen-associated molecular patterns (PAMP), DCs express a number of pattern recognition receptors (PRR) such as Toll-like rec- tors (TLRs) and C-type lectin receptors (CLR) that recognise structural components of pathogens and discriminate between self and non-self molecules.
Product Identifiers
Publisher
Springer-Verlag Berlin AND Heidelberg Gmbh & Co. KG
ISBN-13
9783642090073
eBay Product ID (ePID)
99856121
Product Key Features
Publication Name
Dendritic Cells
Format
Paperback
Language
English
Subject
Medicine
Publication Year
2010
Type
Textbook
Number of Pages
353 Pages
Dimensions
Item Height
235mm
Item Width
155mm
Volume
188
Item Weight
569g
Additional Product Features
Series Title
Handbook of Experimental Pharmacology
Editor
Yanira Riffo-Vasquez, Giovanna Lombardi
Country/Region of Manufacture
Germany
Item description from the seller
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eBay item number:314677341386
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Useful book