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Triple Repeat Diseases of the Nervous Systems - 9781461349310
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Located in: Aldershot, United Kingdom
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eBay item number:314675240387
Item specifics
- Condition
- Brand New: A new, unread, unused book in perfect condition with no missing or damaged pages. See all condition definitionsopens in a new window or tab
- Book Title
- Triple Repeat Diseases of the Nervous Systems
- ISBN
- 9781461349310
- Publication Year
- 2012
- Type
- Textbook
- Format
- Paperback
- Language
- English
- Publication Name
- Triple Repeat Diseases of the Nervous Systems
- Item Height
- 254mm
- Publisher
- Springer-Verlag New York Inc.
- Item Width
- 178mm
- Subject
- Botany, Biology, Physics
- Item Weight
- 271g
- Number of Pages
- 121 Pages
About this product
Product Information
World of Unstable Mutations The book Triplet Repeat Diseases of the Nervous System overviews the lat est data on several disorders associated with unstable mutations. This field of re search is progressing extremely fast. The number of polymorphic mutations and diseases caused by these mutations is increasing almost every month. There is a strong interest to molecular bases of triplet repeat disorders. This is explained by growing necessity to develop molecular approaches for cure of these diseases. There fore, the authors of this book describe unstable mutations with the emphasis on molecular pathology. Broad discussion is presented on how polymorphic expan sions cause cell dysfunction. o The first chapter of the book focuses on the molecular pathological pro cesses that originate unstable mutations. The authors review several avail able models by which normal stable region of DNA become pathogenic and discuss possible mechanisms causing DNA instability. o The other chapters of the book describe inherited diseases associated with different types of unstable mutations. Based on the location of mutation in the disease gene, polymorphic expansions of the nervous system can be divided into two major groups. First group includes disorders with unstable expansions within the open reading frame of the gene such as Spinocer ebellar Ataxias caused by polyglutamine expansions. The second group in cludes diseases caused by expansions situated within the untranslated re gions of the gene.
Product Identifiers
Publisher
Springer-Verlag New York Inc.
ISBN-13
9781461349310
eBay Product ID (ePID)
176770074
Product Key Features
Publication Name
Triple Repeat Diseases of the Nervous Systems
Format
Paperback
Language
English
Subject
Botany, Biology, Physics
Publication Year
2012
Type
Textbook
Number of Pages
121 Pages
Dimensions
Item Height
254mm
Item Width
178mm
Volume
516
Item Weight
271g
Additional Product Features
Series Title
Advances in Experimental Medicine and Biology
Country/Region of Manufacture
United States
Editor
Lubov T. Timchenko
Item description from the seller
Business seller information
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eBay item number:314675240387
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All great, thank you!