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Study on the Cellular Regulation and Function of Lysine Malon... - 9789811525087

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Item specifics

Condition
Brand New: A new, unread, unused book in perfect condition with no missing or damaged pages. See all condition definitionsopens in a new window or tab
Book Title
Study on the Cellular Regulation and Function of Lysine Malony...
ISBN
9789811525087
Publication Name
Study on the Cellular Regulation and Function of Lysine Malonylation, Glutarylation and Crotonylation
Publisher
Springer Verlag, Singapore
Subject
Chemistry, Biology
Series
Springer Theses
Publication Year
2020
Type
Textbook
Format
Hardcover
Language
English
Item Height
235 mm
Author
Xiucong Bao
Item Width
155 mm
Item Weight
448 g
Number of Pages
163 Pages

About this product

Product Information

This book presents pioneering findings on the characterization of cellular regulation and function for three recently identified protein posttranslational modifications (PTMs): lysine malonylation (Kmal), glutarylation (Kglu) and crotonylation (Kcr). It addresses three main topics: (i) Detecting Kmal substrates using a chemical reporter, which provides important information regarding the complex cellular networks modulated by Kmal; (ii) Identifying Kglu as a new histone PTM and assessing the direct impact of histone Kglu on chromatin structure and dynamics; and (iii) Revealing Sirt3's value as a regulating enzyme for histone Kcr dynamics and gene transcription, which opens new avenues for examining the physiological significance of histone Kcr. Taken together, these studies provide information critical to understanding how these protein PTMs are associated with various human diseases, and to identifying therapeutic targets for the dysregulation of these novel protein markers in various human diseases.

Product Identifiers

Publisher
Springer Verlag, Singapore
ISBN-13
9789811525087
eBay Product ID (ePID)
27046596472

Product Key Features

Series
Springer Theses
Author
Xiucong Bao
Publication Name
Study on the Cellular Regulation and Function of Lysine Malonylation, Glutarylation and Crotonylation
Format
Hardcover
Language
English
Subject
Chemistry, Biology
Publication Year
2020
Type
Textbook
Number of Pages
163 Pages

Dimensions

Item Height
235 mm
Item Width
155 mm
Item Weight
448 g

Additional Product Features

Country/Region of Manufacture
Singapore
Title_Author
Xiucong Bao

Item description from the seller

Business seller information

Value Added Tax Number:
  • GB 976952259
BOOKS etc.

BOOKS etc.

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