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Reviews of Physiology, Biochemistry and Pharmacology 147 - 9783642056833
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Located in: Aldershot, United Kingdom
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eBay item number:285350643987
Item specifics
- Condition
- Brand New: A new, unread, unused book in perfect condition with no missing or damaged pages. See all condition definitionsopens in a new window or tab
- Book Title
- Reviews of Physiology, Biochemistry and Pharmacology 147
- ISBN
- 9783642056833
- Publication Year
- 2010
- Type
- Textbook
- Format
- Paperback
- Language
- English
- Publication Name
- Reviews of Physiology, Biochemistry and Pharmacology 147
- Item Height
- 235mm
- Publisher
- Springer-Verlag Berlin AND Heidelberg Gmbh & Co. KG, R. Hogg, J. Eckert, D. Bertrand, B. Ludwig, C. Andersen, M. Raggenbass, O. Richter, R. Erdmann
- Item Width
- 155mm
- Subject
- Medicine
- Item Weight
- 272g
- Number of Pages
- 165 Pages
About this product
Product Information
Ligand-gated ion channels mediate fast synaptic transmission in the central nervous s- tem (CNS) and at ganglionic and neuromuscular synapses. The nicotinic acetylcholine - ceptor (nAChR) is a member of the ligand-gated ion channel superfamily, which includes the 5-HT , glycine and GABA type A and C receptors. These receptors are known as Cys- 3 loop receptors, as all of them have a conserved sequence containing a pair of cysteines separated by 13 residues and linked by a disulfide bridge. nAChRs can be divided into two groups: muscle receptors, which are found at the skeletal neuromuscular junction where they mediate neuromuscular transmission, and neuronal receptors, which are found throughout the peripheral and central nervous system. Many of the early studies carried out on the subunit composition and structure of the nAChRs were performed on receptors isolated from the electric organ of Torpedo californica, as this tissue is very rich in nAChRs, and they were found to have a high degree of homology with the embryonic v- tebrate muscle type receptor. Muscle nAChRs are made up of five subunits arranged around a central pore (Fig. 1A, B). In Torpedo electric organ and vertebrate fetal muscle, the subunit composition is (a1) b1gd, and in adult muscle the g subunit is replaced by the e to give an (a1)b1ed 2 2 composition (Mishina et al. 1986).
Product Identifiers
Publisher
Springer-Verlag Berlin AND Heidelberg Gmbh & Co. KG, R. Hogg, J. Eckert, D. Bertrand, B. Ludwig, C. Andersen, M. Raggenbass, O. Richter, R. Erdmann
ISBN-13
9783642056833
eBay Product ID (ePID)
178224895
Product Key Features
Publication Name
Reviews of Physiology, Biochemistry and Pharmacology 147
Format
Paperback
Language
English
Subject
Medicine
Publication Year
2010
Type
Textbook
Number of Pages
165 Pages
Dimensions
Item Height
235mm
Item Width
155mm
Volume
147
Item Weight
272g
Additional Product Features
Series Title
Reviews of Physiology, Biochemistry and Pharmacology
Country/Region of Manufacture
Germany
Item description from the seller
Business seller information
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- GB 976952259
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eBay item number:285350643987
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