Steroid Enzymes and Cancer (Annals of the - Paperback, by Bradlow H. Leon - Good

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Item specifics

Condition
Good: A book that has been read but is in good condition. Very minimal damage to the cover including ...
Book Title
Steroid Enzymes and Cancer (Annals of the New York Academy of Sci
ISBN
9781573317450
Category

About this product

Product Identifiers

Publisher
Wiley & Sons, Incorporated, John
ISBN-10
1573317454
ISBN-13
9781573317450
eBay Product ID (ePID)
72355169

Product Key Features

Number of Pages
352 Pages
Publication Name
Steroid Enzymes and Cancer, Volume 1155
Language
English
Subject
Oncology, Endocrinology & Metabolism, Chemistry / Organic
Publication Year
2009
Type
Textbook
Subject Area
Science, Medical
Author
Guiseppe Carruba
Series
Annals of the New York Academy of Sciences Ser.
Format
Trade Paperback

Dimensions

Item Height
0.6 in
Item Weight
25.3 Oz
Item Length
10 in
Item Width
7 in

Additional Product Features

Intended Audience
Scholarly & Professional
LCCN
2009-003009
Dewey Edition
22
Reviews
'The articles are written by authorities in their respective research areas, and they provide good coverage of steroid enzymes in cancer. Most of the authors represent research groups that are acknowledged leaders in their fields.' ( Doody's , November 2009), ?The articles are written by authorities in their respective research areas, and they provide good coverage of steroid enzymes in cancer. Most of the authors represent research groups that are acknowledged leaders in their fields.? ( Doody?s , November 2009)
Illustrated
Yes
Volume Number
Vol. 1155
Dewey Decimal
616.99/4061
Synopsis
The expression and activity of key enzymes of sex steroid metabolism have major implications in both development and progression of various human hormone-related tumors, including breast, prostate, lung, and liver cancer. This volume explores the role of local synthesis of steroid hormones, a process that has assumed an increasing importance in our understanding about several malignancies originating from steroid target tissues, wherein abnormal levels of individual steroids may promote tumor growth. In this framework, a divergent expression and/or activity of key gonadal steroid enzymes (including dehydrogenases, hydroxylases, sulfotransferases, sulfatases, and aromatase) may eventually lead to a differential accumulation of hormone derivatives with divergent biological activities in individual target tissues. This is of crucial importance in predicting the overall biological impact that sex steroids have on peripheral target tissues and, hence, on their potential role in cancer development and/or progression. The volume focuses on five key enzymes in the metabolism of sex steroids: (1) 17 hydroxysteroid dehydrogenase; (2) 5 reductase; (3) hydroxylases and catechol-oxy methyltransferase; (4) sulfatase, sulfotransferases, and glucuronidase; and (5) aromatase. The organization of the volume is designed to provide an updated picture of the existing knowledge about the association between steroid enzyme expression/function and the development and/or progression of major human cancers, including classical (breast, prostate) and nonclassical (lung, liver) hormone-related tumors. The resulting inferences for diagnosis, prognosis, and treatment are also presented, along with the experimental basis for developing preventive measures. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas . ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order ( www.nyas.org ). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit www.nyas.org/membership/main.asp for more information about becoming a member., The expression and activity of key enzymes of sex steroid metabolism have major implications in both development and progression of various human hormone-related tumors, including breast, prostate, lung, and liver cancer. This volume explores the role of local synthesis of steroid hormones, a process that has assumed an increasing importance in our understanding about several malignancies originating from steroid target tissues, wherein abnormal levels of individual steroids may promote tumor growth. In this framework, a divergent expression and/or activity of key gonadal steroid enzymes (including dehydrogenases, hydroxylases, sulfotransferases, sulfatases, and aromatase) may eventually lead to a differential accumulation of hormone derivatives with divergent biological activities in individual target tissues. This is of crucial importance in predicting the overall biological impact that sex steroids have on peripheral target tissues and, hence, on their potential role in cancer development and/or progression. The volume focuses on five key enzymes in the metabolism of sex steroids: (1) 17hydroxysteroid dehydrogenase; (2) 5reductase; (3) hydroxylases and catechol-oxy methyltransferase; (4) sulfatase, sulfotransferases, and glucuronidase; and (5) aromatase. The organization of the volume is designed to provide an updated picture of the existing knowledge about the association between steroid enzyme expression/function and the development and/or progression of major human cancers, including classical (breast, prostate) and nonclassical (lung, liver) hormone-related tumors. The resulting inferences for diagnosis, prognosis, and treatment are also presented, along with the experimental basis for developing preventive measures. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas . ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order ( www.nyas.org ). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http: //www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member., This volume is designed to provide an updated picture of the existing knowledge about the association between steroid enzyme expression/function and the development and/or progression of major human cancers, including classical (breast, prostate) and nonclassical (lung, liver) hormone-related tumors., The expression and activity of key enzymes of sex steroid metabolism have major implications in both development and progression of various human hormone-related tumors, including breast, prostate, lung, and liver cancer. This volume explores the role of local synthesis of steroid hormones, a process that has assumed an increasing importance in our understanding about several malignancies originating from steroid target tissues, wherein abnormal levels of individual steroids may promote tumor growth. In this framework, a divergent expression and/or activity of key gonadal steroid enzymes (including dehydrogenases, hydroxylases, sulfotransferases, sulfatases, and aromatase) may eventually lead to a differential accumulation of hormone derivatives with divergent biological activities in individual target tissues. This is of crucial importance in predicting the overall biological impact that sex steroids have on peripheral target tissues and, hence, on their potential role in cancer development and/or progression. The volume focuses on five key enzymes in the metabolism of sex steroids: (1) 17βhydroxysteroid dehydrogenase; (2) 5αreductase; (3) hydroxylases and catechol-oxy methyltransferase; (4) sulfatase, sulfotransferases, and glucuronidase; and (5) aromatase. The organization of the volume is designed to provide an updated picture of the existing knowledge about the association between steroid enzyme expression/function and the development and/or progression of major human cancers, including classical (breast, prostate) and nonclassical (lung, liver) hormone-related tumors. The resulting inferences for diagnosis, prognosis, and treatment are also presented, along with the experimental basis for developing preventive measures. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas . ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order ( www.nyas.org ). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member.
LC Classification Number
RC268.2.A38 2009

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